How Do Bug Sprays (Like Raid And Baygon) Kill Cockroaches?

Table of Contents (click to expand)

Contrary to popular belief, cockroaches cannot survive a nuclear explosion; however, it is true that cockroaches are more tolerant of certain ionizing radiation than humans. Even so, they cannot survive bug spray, as it consists of powerful neurotoxic substances.

Cockroaches are quite amazing creatures. People who shrink at the sight of these little insects may not share this opinion, but if you look at the feats that cockroaches are capable of achieving, you would agree too… probably.

A cockroach can hold its breath for almost 40 minutes, so there’s little hope of drowning them. It can survive a few days without water, a month without food, and even a few weeks without a head!

Contrary to popular belief, cockroaches cannot survive a nuclear explosion any more than they can survive an onslaught from their deadly enemy – bug spray.

The likes of Raid, Hit, Baygon, and other popular brands are fatal to these roaches. So, how do these insecticides kill such tough and durable insects so quickly?

Recommended Video for you:

What Are Insecticides?

Bug sprays or insecticides are chemical compounds that inhibit certain physiological functions.

Humans have been using insecticides derived from natural sources since ancient times. Most of these strategies originally came from plant chemicals or chemicals such as sulfur or sodium chlorate. Today, we have a wide arsenal of insecticides that we can spray to eliminate our bug problems. The origin of our modern anti-pest weaponry began in the 1940s with DDT and other synthetic chemicals.

The first generation of synthetic pesticides was not created to be pesticides. DDT was first synthesized in 1874 by the chemist Othmar Ziedler, but it was not until 1939 that Dr. Paul Muller observed its pesticidal properties. This discovery and the Second World War played a major role in accelerating the discovery of synthetic pesticides.

Synthetic pesticides were much more efficient and could be used specifically against pests, giving synthetic pesticides an edge over those used in the past.

A bug spray. Notice the composition printed on its cover.
A bug spray. Notice the composition printed on its cover.

Insecticides can be lethal in various ways: some act as neurotoxins, impairing the nervous system; others target respiration and prevent the insect from utilizing oxygen; and others target the insect’s growth and reproduction.

Also Read: What Are Biopesticides?

Types Of Insecticides

Many classes of insecticides differ in their synthesis, how they affect the pest, and whether they indiscriminately affect all insects or are specific to a particular type or family.

Insecticides can be lethal in various ways: some act as neurotoxins, impairing the nervous system; others target respiration and prevent the insect from utilizing oxygen; and others target the insect’s growth and reproduction.

Popular roach-killing bug sprays are a concoction of several pesticides that fall under two broad types: pyrethroids and carbamates.

Also Read: Why Do Cockroaches Die On Their Backs?

Pyrethroids Are Neurotoxic For Insects.

Pyrethroids are fast-acting compounds found in most household insecticides and insect repellents. Pyrethroids are synthetic compounds but resemble a natural pesticide made from daisy flowers called pyrethrin.

Pyrethrin is extracted from the ‘Pyrethrum daisy,’ Chrysanthemum cinerariaefolium. The crushed flower has been used as an insecticide for over 2,000 years. Inhaling too much of the flower’s scent is harmful as it can cause side effects such as asthmatic breathing, sneezing, and headaches. Pyrethroids are chemically similar to pyrethrin but synthetically produced.

Pyrethroids are neurotoxic and impair the function of the neurons in a cockroach, thereby paralyzing it. The chemicals target proteins that transport sodium and potassium across the neuron membrane. Neurons can send impulses through the controlled entry and exit of these ions through the appropriate protein channels. Pyrethroids interfere with these channels and keep them open, impairing the functioning of the neuron.

Another reason why pyrethroids are a popular choice for bug sprays is that a very low dose of pyrethroids can kill cockroaches. The same concentration is relatively harmless to humans. However, they can harm sensitive individuals or aquatic organisms such as fish when used directly in water, as they dissolve very poorly.

allehtrin structure
The structural formula of Allethrin, a synthetic pyrethroid commonly found in bug sprays.

Some commonly used pyrethroids include allethrin, tetramethrin, resmethrin, cyfluthrin, permethrin, and esfenvalerate. Also known as ‘first-generation pyrethroids’, these were primarily developed in the 1940s.

Also Read: How Do Mosquito Repellents Work? How Do They Keep Mosquitoes From Biting Us?

Carbamates Inhibit Enzymes In The Nervous System.

The other once-common chemical pesticide component of bug spray that is now used less often is carbamate. This class of pesticide is derived from carbonic acid.

These compounds target a specific enzyme called acetylcholinesterase. This enzyme plays a role in breaking down the neurotransmitter, a chemical messenger of the nervous system called acetylcholine. Neurons release acetylcholine to communicate with other neurons and muscles, giving the latter a signal to contract.

In normal function, the body allows acetylcholine to be present in the extracellular environment for a very short period. The cholinesterase enzyme breaks down the acetylcholine molecule, thereby preventing prolonged signaling to other neurons and muscles.

Carbamates prevent acetylcholinesterases from breaking down acetylcholine. As a result, the molecule constantly stimulates other neurons, which makes the muscles contract. Not only do the muscles involved in walking and moving paralyze, but the muscles of the heart and those involved in respiration seize, too.

Unable to move, breathe, or circulate blood, the cockroach dies.

Insect Resistance: Cockroaches Fight Back

These and thousands of other insecticides are employed today to keep our homes, gardens, and crops safe from a range of pests, and their use has improved our standard of living and increased crop yields, but there are a few downsides to the story.

Cockroaches, being cockroaches, are outsmarting us. The German cockroach (Blattella germanica), a worldwide pest known to spread diseases and carry allergens, is the only roach developing insecticide resistance. A la Tom and Jerry, no sooner have we set up an insecticide trap than the roaches have evolved to resist it, a result of our more than liberal approach to bug sprays and how quickly the insect reproduces.

In 2019, scientists from Purdue University published some concerning results. They report that, in some instances, resistance to one insecticide also gave the roach resistance to another class of insecticide, limiting the cocktail of chemicals we can spray on these critters.

It gets worse. Researchers Ayako Wada-Katsumata, Jules Silverman and Coby Schal discovered that the German cockroach had evolved a dislike for sugar. Cockroaches love sugar. This made sugar the perfect bait. As cheese is to a rat, so too sugar is to a cockroach. But, the researchers found that roaches who survived the sugar bait did so because they had a mutation that made sugar taste bitter. If you avoid the bait, you don’t die.

Also Read: What If There Were No Cockroaches?

Overusing Insecticides Isn’t Good For The Environment

Many of these pesticides remain in the soil and body of the animals that could inhale or consume them. If other animals feed on insects that have ingested the pesticide or drink water from places where insecticides are present, these animals often have unintended effects. This is known as the bioaccumulation of pesticides.

The prolific environmentalist Rachel Carson cautioned our world against the excessive use of pesticides. In her revolutionary book Silent Spring, she writes, “A Who’s Who of pesticides is therefore of concern to us all. If we are going to live so intimately with these chemicals, eating and drinking them, taking them into the very marrow of our bones – we had better know something about their nature and their power.”

Last Updated By: Salama Yusuf

References (click to expand)
  1. Soderlund, D. M. (2011, June 28). Molecular mechanisms of pyrethroid insecticide neurotoxicity: recent advances. Archives of Toxicology. Springer Science and Business Media LLC.
  2. Biotechnology and Biological Sciences Research Council (BBSRC) -
  3. History of Pesticide Use.
  4. Insecticides | US EPA.
  5. Insecticide Basics.
  6. Wada-Katsumata, A., Silverman, J., & Schal, C. (2013, May 24). Changes in Taste Neurons Support the Emergence of an Adaptive Behavior in Cockroaches. Science. American Association for the Advancement of Science (AAAS).
  7. Fardisi, M., Gondhalekar, A. D., Ashbrook, A. R., & Scharf, M. E. (2019, June 5). Rapid evolutionary responses to insecticide resistance management interventions by the German cockroach (Blattella germanica L.). Scientific Reports. Springer Science and Business Media LLC.
  8. Soderlund, D. M. (2011, June 28). Molecular mechanisms of pyrethroid insecticide neurotoxicity: recent advances. Archives of Toxicology. Springer Science and Business Media LLC.
About the Author

Ashish is a Science graduate (Bachelor of Science) from Punjabi University (India). He spearheads the content and editorial wing of ScienceABC and manages its official Youtube channel. He’s a Harry Potter fan and tries, in vain, to use spells and charms (Accio! [insert object name]) in real life to get things done. He totally gets why JRR Tolkien would create, from scratch, a language spoken by elves, and tries to bring the same passion in everything he does. A big admirer of Richard Feynman and Nikola Tesla, he obsesses over how thoroughly science dictates every aspect of life… in this universe, at least.

   -   Contact Us